منابع مشابه
Hemoglobin (Hb) Stanleyville II causes gross overestimation of the Hb A1c proportion in routine HPLC.
duction in neutrophils is induced by G-CSF, and NAP is released into the bloodstream, perhaps through leakage of ALP from damaged or dead neutrophils. Fossa et al. (9 ) reported leukocytosis and increased serum ALP in response to G-CSF treatment and suggested that increased serum ALP activity was related to release of the enzyme from the increased numbers of leukocytes. Neutrophils were reporte...
متن کاملThe role and quality of hb a1c: a continuing evolution.
Since glycohemoglobin was first described in the red cells of diabetes patients in 1968 (1 ), the test has evolved to become an essential tool for prognosis, monitoring, treatment, and diagnosis of diabetes mellitus. An increasing clinical focus together with the development of diabetes management guidelines based on glycated hemoglobin (Hb A1c) 2 necessitated a standardization of the method in...
متن کاملPerformance of the Roche second generation hemoglobin A1c immunoassay in the presence of HB-S or HB-C traits.
Blood HbA1c determination is a powerful tool for the evaluation and management of patients with diabetes mellitus. Many HbA1c analytical methods demonstrate bias in samples from patients with hemoglobinopathies. This study evaluated the analytical performance of Roche Diagnostics' 1st and 2nd generation HbA1c assays in patients with or without hemoglobinopathies whose HbA1c levels were elevated...
متن کاملIncidence of variant hemoglobin (Hb) and increased fetal Hb concentrations and their effect on Hb A1c measurement in a Korean population.
To the Editor: Glycohemoglobin assays are important for evaluating long-term glycemic control in patients with diabetes (1 ). Ion-exchange HPLC is commonly used for measuring hemoglobin A1c (Hb A1c), but hemoglobin variants (Hb) or increased fetal Hb concentrations may affect the quantification of Hb A1c by HPLC. The presence of Hb or high Hb F concentrations can be recognized by the separate e...
متن کاملMeasurment of stable Glycosylated Hemoglobin (Hb A1) and Its unstable type (pre- Hb A1c) with the lon- exchange Chromatography in Diabetic patients
SUMMARY: At present, measurment of glycosylated hemoglobin, especially the stable fraction of hemoglobin (HbA1c) is one of the ways to control diabetes because this measurment can demonstrate total glycemia during last 1.2.3 months. Glycosylated hemoglobin is seen in 3 forms: Ala Alb A1c. Among these hemoglobin Alc is quantitively more than other 2 forms and its difference with other hemoglobi...
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ژورنال
عنوان ژورنال: Swiss Medical Forum ‒ Schweizerisches Medizin-Forum
سال: 2005
ISSN: 1424-4020,1424-3784
DOI: 10.4414/smf.2005.05690